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CEEHRC / About Epigenetics /
Mouse Model
Epigenetics and drug addiction: predisposition, chronic use, relapse and treatment

For those who have not experienced drug addiction, it can be easy to view the disease as a choice—but research shows that epigenetics plays an important role.

Mouse Sperm on a Counting Chamber
Epigenetic alteration of the young dark matter in sperm worsens fertility across two successive generations

Loss of DNA methylation at transposable elements in sperm is associated with decreased sperm function in the offspring.

galloy
Scientist Spotlight: Maxime Galloy, Université Laval

Maxime Galloy works on deciphering how the chromatin composition surrounding the DNA damage impact the repair.

prostate cancer
Prostate Cancer Lineage Plasticity is Driven by Epigenetic Alterations

Epigenetic plasticity drives castration-resistant prostate cancer (CRPC) to neuroendocrine prostate cancer (NEPC) transition, marked by chromatin remodeling and DNA methylation changes

Oncohistones
Oncohistones; Epigenetic drivers of Cancer and Beyond

This article introduces oncohistones and provides a brief overview of commonly studied oncohistone mutations and their involvement in cancer.

Juan Zhang
Scientist Spotlight: Juan Zhang, University of Toronto

Juan works on repetitive elements for their potential roles in chromatin organization during early embryonic development

Kailynn MacGillivray
Scientist Spotlight: Kailynn MacGillivray, University of Toronto

Kailynn MacGillivray works on histone modifications in C. elegans

Louis-Alexandre Fournier
Scientist Spotlight: Louis-Alexandre Fournier, University of British Columbia

Louis-Alexandre Fournier works on regulation of DNA organization within the cell.

Catfur
Cat fur and color blindness: what X-chromosome inactivation teaches us about health

The epigenetic inactivation of the X chromosome during embryonic development drives major biological processes – for us and for our favorite pets.