For those who have not experienced drug addiction, it can be easy to view the disease as a choice—but research shows that epigenetics plays an important role.
Loss of DNA methylation at transposable elements in sperm is associated with decreased sperm function in the offspring.
Maxime Galloy works on deciphering how the chromatin composition surrounding the DNA damage impact the repair.
Epigenetic plasticity drives castration-resistant prostate cancer (CRPC) to neuroendocrine prostate cancer (NEPC) transition, marked by chromatin remodeling and DNA methylation changes
This article introduces oncohistones and provides a brief overview of commonly studied oncohistone mutations and their involvement in cancer.
Juan works on repetitive elements for their potential roles in chromatin organization during early embryonic development
Kailynn MacGillivray works on histone modifications in C. elegans
Louis-Alexandre Fournier works on regulation of DNA organization within the cell.
The epigenetic inactivation of the X chromosome during embryonic development drives major biological processes – for us and for our favorite pets.